跳至主要内容

Is silicone oil safe?

Is silicone oil safe?

From a physiological point of view, polysiloxane is one of the polymers with the lowest known activity. The results of toxicological studies suggest that dimethyl silicone oil, which removes low-boiling substances, is non-toxic and can be used in large amounts in food,

cosmetics, and pharmaceuticals. The LD50 value (50% lethal amount) of the lethal dose of dimethyl silicone oil is more than 35g/Kg. This value is classified according to the toxicity of the American Industrial Hygiene Association, which is equivalent to non-toxic; it also has no chronic poisoning problems and will not be absorbed by the digestive system. No irritation to the membrane; low viscosity dimethyl silicone oil has slight irritation to the cornea, but no harm.

Safety data of silicone oil as follow:

Types of silicone oil

Viscosity (25°C/mm2Ÿs)

Skin irritation (human)

Chronic toxicity (rat, 6 months)

Acute toxicity LD50 (rat, administered orally)

Eye irritation (Japanese white rabbit)

Methyl hydrogen silicone oil

5

Quasi-negative

---

>33ML/kg

Very slight

10

Negative

No abnormality [input amount 10mL/(kg·d)]

---

---

20

---

---

>50g/kg

---

100

Negative

---

---

---

Methyl phenyl silicone oil (phenyl mole fraction 25%)

20

Quasi-negative

---

>33ML/kg

Very slight

Methylphenyl silicone oil (phenyl mole fraction 50%)

400

---

---

30g/kg

---

Methyl hydrogen silicone oil

---

---

---

>33ML/kg

---

*  No effect on cornea; slight inflammation on conjunctiva, but less irritating than normal detergent.

It should be noted that the production method and production environment of silicone oil affect the purity of silicone oil (including low-molecular-weight siloxanes remaining in the silicone oil, catalyst decomposition, neutralization residues and impurities brought into the production environment). For medicine, food and cosmetics, special grade silicone oil should be used. At present, the country has promulgated the National Food Safety Standard for Food Additives Dimethicone and Its Emulsions (GB 30612-2014). Special grade silicone oil for production license.

https://www.linkedin.com/company/china-defoamer

https://invelydefoamer.blogspot.com/

https://www.facebook.com/invelychem/


标签：

评论

发表评论

此博客中的热门博文

How do we assess antifoam efficiency ?

How do we assess antifoam efficiency ? Quality of an antifoam is given by two main characteristics : • Knockdown ability or shock effect :Meaning the speed to destroy an existing foam. • Persistence or durability : Meaning the efficiency over time.   These two parameters can be assessed by several tests. The main test is the bubbling method. A graduated column with a glass frit in the bottom is required. Foaming water is poured in the column and air at constant flowrate is introduced through the glass frit in the column. Foam is generated by the air and starts to travel up the column. At a determined level of foam, antifoam is injected. By this method several antifoaming agents can be tested. A graph reporting foam height vs time is very helpful to establish the knockdown ability and the persistence for each product. The selected antifoam is the product with the best compromise between shock effect and durability       Environmental performance   Silicone antifo...
1 条评论
阅读全文

What is a defoamer / deaerator’s purpose in the system?

What is a defoamer / deaerator’s purpose in the system? Defoamers prevent formation of foam during manufacture and application of coatings and printing inks. Foam that is already formed is destroyed and air occlusions are prevented. Deaerators prevent development of air occlusions and pinholes. Why use a defoamer? The occurrence of foam is considered an undesirable but unavoidable phenomenon in coatings and printing inks. The formation of foam interrupts production processes, reduces the effective volumes in the production plant, and leads to unnecessary down time. Foam also interferes with the application process. In printing, foam can cause the ink reservoirs to overflow and can impair ink transfer from the printing cylinder to the substrate. Dried foam leaves surface defects in the paint film. To prevent foam and destroy any foam present, defoamers must be added to the formulation. defoamer vs. deaerator? To eliminate macro-foam on the surface, to prevent air occlusions, and...
发表评论
阅读全文

Defoamer Test Method

Defoamer testing methods are divided into dynamic defoaming and static defoaming tests. If your foaming environment is different, the recommended test methods are different. There are three main types of foam experiments to characterize the activity of defoamers. Persistence. As we have different experimental conditions in different laboratories and the experiments used in our research to obtain results from existing literature, we will introduce these experiments below. Other methods are sometimes used depending on the particular application. 1． Ross-Miles Foam Tester   Features: Tested for strong foaming environments. This experiment is widely used for characterization        (1) Foaming of surfactant solution        (2) Research and application of foam stability in the presence of defoamer In the foaming system, the defoaming performance test was carried out by circulating bubbling by a Ros...
发表评论
阅读全文