Is silicone oil safe?
Safety data of silicone oil as follow:
Types of silicone oil |
Viscosity (25°C/mm2s) |
Skin irritation (human) |
Chronic toxicity (rat, 6
months) |
Acute toxicity LD50 (rat,
administered orally) |
Eye irritation (Japanese white
rabbit) |
Methyl hydrogen silicone oil |
5 |
Quasi-negative |
--- |
>33ML/kg |
Very slight |
10 |
Negative |
No abnormality [input amount 10mL/(kg·d)] |
--- |
--- |
|
20 |
--- |
--- |
>50g/kg |
--- |
|
100 |
Negative |
--- |
--- |
--- |
|
Methyl phenyl silicone oil
(phenyl mole fraction 25%) |
20 |
Quasi-negative |
--- |
>33ML/kg |
Very slight |
Methylphenyl silicone oil
(phenyl mole fraction 50%) |
400 |
--- |
--- |
30g/kg |
--- |
Methyl hydrogen silicone oil |
--- |
--- |
--- |
>33ML/kg |
--- |
No effect on cornea; slight
inflammation on
conjunctiva, but less irritating than normal detergent.
It should be
noted that the production method and production environment of silicone oil
affect the purity of silicone oil (including low-molecular-weight siloxanes
remaining in the silicone oil, catalyst decomposition, neutralization residues
and impurities brought into the production environment). For medicine, food and
cosmetics, special grade silicone oil should be used. At present, the country
has promulgated the National Food Safety Standard for Food Additives
Dimethicone and Its Emulsions (GB 30612-2014). Special grade silicone oil for
production license.
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